Enhancing metformin-induced tumor metabolism destruction by glucose oxidase for triple-combination therapy

• Main Authors: Rangrang Fan (Author), Linrui Cai (Author), Hao Liu (Author), Hongxu Chen (Author), Caili Chen (Author), Gang Guo (Author), Jianguo Xu (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite decades of laboratory and clinical trials, breast cancer remains the main cause of cancer-related disease burden in women. Considering the metabolism destruction effect of metformin (Met) and cancer cell starvation induced by glucose oxidase (GOx), after their efficient delivery to tumor sit...