Dexamethasone Induces the Expression and Function of Tryptophan-2-3-Dioxygenase in SK-MEL-28 Melanoma Cells

• Asıl Yazarlar: Marta Cecchi (Yazar), Sara Paccosi (Yazar), Angela Silvano (Yazar), Ali Hussein Eid (Yazar), Astrid Parenti (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed enzyme, indoleamine-2,3-dioxygenase-1 (IDO1), do not provide benefits in melano...