Dexamethasone Induces the Expression and Function of Tryptophan-2-3-Dioxygenase in SK-MEL-28 Melanoma Cells

Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed enzyme, indoleamine-2,3-dioxygenase-1 (IDO1), do not provide benefits in melano...

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Main Authors: Marta Cecchi (Author), Sara Paccosi (Author), Angela Silvano (Author), Ali Hussein Eid (Author), Astrid Parenti (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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