Chlorpheniramine Potentiates the Analgesic Effect in Migraine of Usual Caffeine, Acetaminophen, and Acetylsalicylic Acid Combination

• Main Authors: Victor A. Voicu (Author), Ion Mircioiu (Author), Roxana Sandulovici (Author), Constantin Mircioiu (Author), Cristina Plesa (Author), Bruno S. Velescu (Author), Valentina Anuta (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous studies indicated that addition of the antihistaminic chlorpheniramine to the usual combination of acetylsalicylic acid, acetaminophen, and caffeine further increases their synergism both in terms of anti-inflammatory and analgesic effect. The present non-interventional study tested the sup...