Multi-Trait Body Shape Phenotypes and Breast Cancer Risk in Postmenopausal Women: A Causal Mediation Analysis in the UK Biobank Cohort

• Main Authors: Amina Amadou (Author), Heinz Freisling (Author), Anja M. Sedlmeier (Author), Patricia Bohmann (Author), Emma Fontvieille (Author), Andrea Weber (Author), Julian Konzok (Author), Michael J. Stein (Author), Laia Peruchet-Noray (Author), Anna Jansana (Author), Hwayoung Noh (Author), Mathilde His (Author), Quan Gan (Author), Hansjörg Baurecht (Author), Béatrice Fervers (Author)
• Format: Book
• Published: Springer, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Body shape phenotypes combining multiple anthropometric traits have been linked to postmenopausal breast cancer (BC). However, underlying biological pathways remain poorly understood. This study investigated to what extent the associations of body shapes with postmenopausal BC risk is media...