Metastasis-associated fibroblasts: an emerging target for metastatic cancer

• Main Authors: Zimu Wang (Author), Jiaxin Liu (Author), Hairong Huang (Author), Mingxiang Ye (Author), Xinying Li (Author), Ranpu Wu (Author), Hongbing Liu (Author), Yong Song (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Metastasis suggests a poor prognosis for cancer patients, and treatment strategies for metastatic cancer are still very limited. Numerous studies have shown that cancer-associated fibroblasts (CAFs), a large component of the tumor microenvironment, contribute to tumor metastasis. Stromal fi...