Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone-Treated Rats Are Not Affected by Chronic Imipramine Treatment: Possible Involvement of Enhanced 5-HT2A-Receptor Expression in the Frontal Cortex

• Main Authors: Yoshihisa Kitamura (Author), Kazuhiko Shibata (Author), Kozue Akiyama (Author), Shizue Kimoto (Author), Yoshika Fujitani (Author), Kouhei Kitagawa (Author), Hirotaka Kanzaki (Author), Mamoru Ouchida (Author), Kenji Shimizu (Author), Hiromu Kawasaki (Author), Toshiaki Sendo (Author), Yutaka Gomita (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined the influence of imipramine, a traditional tricyclic antidepressant, on the binding to serotonin (5-HT)2receptors and levels of 5-HT2A-receptor mRNA in the frontal cortex of rats treated with adrenocorticotropic hormone (ACTH). Chronic treatment with ACTH significantly increased the bind...