Nobiletin restores HFD-induced enteric nerve injury by regulating enteric glial activation and the GDNF/AKT/FOXO3a/P21 pathway
Abstract Background To explore whether nobiletin has a protective effect on high-fat diet (HFD)-induced enteric nerve injury and its underlying mechanism. Methods An obesity model was induced by a HFD. Nobiletin (100 mg/kg and 200 mg/kg) and vehicle were administered by gastric gavage for 4 weeks. L...
Saved in:
Main Authors: | Yueshan Pang (Author), Li Zhang (Author), Zhuoting Zhong (Author), Ni Yang (Author), Yali Zheng (Author), Weijun Ding (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2024-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Aberrant Development of Enteric Glial Cells in the Colon of Hirschsprung's Disease
by: Tingting Zhou, et al.
Published: (2021) -
Treatment with glial derived neurotropic factor (GDNF) attenuates oxidative damages of spinal
by: Tao Li, et al.
Published: (2016) -
Tryptase activates enteric glial cells followed by affecting neuronal properties possibly via the stimuli-associated mediators
by: Kazunari Tominaga, et al.
Published: (2023) -
Hyperglycemic stress induces oxidative damage of enteric glial cells by triggering redoxosomes/p66SHC activation
by: Yanmin Jiang, et al.
Published: (2024) -
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation
by: Kouminin Kanwore, et al.
Published: (2023)