Novel heterocyclic hybrid of 2-(aryl)-1H-indene-1,3(2H)-dione targeting tyrosinase: design, biological evaluation and in silico studies
Melanogenesis is a process of melanin synthesize, which is a primary response for the pigmentation of human skin. Tyrosinase is a key enzyme, which catalyzes a rate-limiting step of the melanin formation, natural products have shown potent inhibitors, but some of these possess toxicity. Numerous syn...
Saved in:
Main Authors: | Aida Iraji (Author), Ali Nemati (Author), Hona Hosseinpoor (Author), Najmeh Edraki (Author), mahsima Khoshneviszadeh (Author), Mahshid Attarroshan (Author), Hossein Sadeghpour (Author), Mehdi Khoshneviszadeh (Author) |
---|---|
Format: | Book |
Published: |
Shiraz University of Medical Sciences,
2020-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Benzylidene-6-hydroxy-3,4-dihydronaphthalenone chalconoids as potent tyrosinase inhibitors
by: Sara Ranjbar, et al.
Published: (2021) -
Design, synthesis and biological evaluation of novel 2-hydroxy-1 H-indene-1,3(2 H)-dione derivatives as FGFR1 inhibitors
by: Mohammed M. Al-Mahadeen, et al.
Published: (2024) -
Design, synthesis, cytotoxicity evaluation and docking studies of 1,2,4-triazine derivatives bearing different arylidene-hydrazinyl moieties as potential mTOR inhibitors
by: Sara Ranjbar, et al.
Published: (2018) -
Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency
by: Shengtao Xu, et al.
Published: (2023) -
Assessment of Anti-tyrosinase and Antioxidant Activities along with Molecular Docking Studies, and in silico ADME of Some 3-Hydroxypyridin-4-one Derivatives
by: Fateme Zare, et al.
Published: (2024)