Mechanically Robust Gastroretentive Drug-Delivery Systems Capable of Controlling Dissolution Behaviors of Coground β-Lapachone

• Päätekijät: Hyeongmin Kim (Tekijä), Chung-Lyol Lee (Tekijä), Seohyun Lee (Tekijä), Tae Jin Lee (Tekijä), Iqra Haleem (Tekijä), Younghong Lee (Tekijä), Na Jung Hwang (Tekijä), Kyusun Shim (Tekijä), Dohyun Kim (Tekijä), Jaehwi Lee (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2019-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

In this study, we aimed to design a highly swellable and mechanically robust matrix tablet (SMT) as a gastroretentive drug-delivery system (GRDDS) capable of improving the dissolution behavior of β-lapachone with low aqueous solubility. For the preparation of SMTs, the cogrinding technique and freez...