Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic-Inorganic Structure with High Medicinal Significance

• Main Authors: Mirela-Fernanda Zaltariov (Author), Mihaela Turtoi (Author), Dragos Peptanariu (Author), Ana-Maria Macsim (Author), Lilia Clima (Author), Corneliu Cojocaru (Author), Nicoleta Vornicu (Author), Bianca-Iulia Ciubotaru (Author), Alexandra Bargan (Author), Manuela Calin (Author), Maria Cazacu (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two chemical motifs of interest for medicinal chemistry, silatrane as 1-(3-aminopropyl) silatrane (SIL M), and nitro group attached in position 5 to salicylaldehyde, are coupled in a new structure, 1-(3-{[(2-hydroxy-5-nitrophenyl)methylidene]amino}propyl)silatrane (SIL-BS), through an azomethine moi...