Solid Lipid Microparticles by Spray Congealing of Water/Oil Emulsion: An Effective/Versatile Loading Strategy for a Highly Soluble Drug

• Autores principales: Alessandro Candiani (Autor), Andrea Milanesi (Autor), Andrea Foglio Bonda (Autor), Giada Diana (Autor), Elia Bari (Autor), Lorena Segale (Autor), Maria Luisa Torre (Autor), Lorella Giovannelli (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Spray congealing technique was exploited to produce solid lipid microparticles (SLMp) loaded with a highly water-soluble drug (metoclopramide hydrochloride) dissolved in the aqueous phase of a water in oil (W/O) emulsion. The use of an emulsion as starting material for a spray congealing treatment i...