Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

• Prif Awduron: Mitsutaka Yakabe (Awdur), Tatsuya Hosoi (Awdur), Hiroko Sasakawa (Awdur), Masahiro Akishita (Awdur), Sumito Ogawa (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2022-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Muscle disuse results in loss of skeletal muscle mass and function. Hochu-ekki-to (TJ-41; Bu-Zhong-Yi-Qi-Tang in Chinese) is an herbal medicinal formulation used to treat patients with frailty, fatigue and appetite loss. It has been suggested that two atrogenes, atrogin-1 and mus...