Metabolic Stability and Metabolite Characterization of Capilliposide B and Capilliposide C by LC-QTRAP-MS/MS

• Main Authors: Zhongzhe Cheng (Author), Xing Zhou (Author), Zhifeng Du (Author), Wenyi Li (Author), Bingying Hu (Author), Jingkui Tian (Author), Lin Zhang (Author), Jiangeng Huang (Author), Hongliang Jiang (Author)
• Format: Book
• Published: MDPI AG, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Capilliposide B (LC-B) and Capilliposide C (LC-C), two new triterpenoid saponins extracted from Lysimachia capillipes Hemsl, exhibit potential anticancer activity both in vitro and in vivo. However, their metabolic process remains unclear. In this study, the metabolic stability of LC-B, LC-C, and Ca...