Artificial tumor microenvironment regulated by first hemorrhage for enhanced tumor targeting and then occlusion for synergistic bioactivation of hypoxia-sensitive platesomes

• Main Authors: Wenhui Tao (Author), Dongyang Zhao (Author), Guanting Li (Author), Lingxiao Li (Author), Songhao Li (Author), Hao Ye (Author), Chutong Tian (Author), Yutong Lu (Author), Shuying Li (Author), Yinghua Sun (Author), Zhonggui He (Author), Jin Sun (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The unique characteristics of the tumor microenvironment (TME) could be exploited to develop antitumor nanomedicine strategies. However, in many cases, the actual therapeutic effect is far from reaching our expectations due to the notable tumor heterogeneity. Given the amplified characteristics of T...