Losartan Inhibits Nuclear Factor-κB Activation Induced by Small, Dense LDL Cholesterol Particles in Human Umbilical Vein Endothelial Cells

• প্রধান লেখক: Gonghui Guo, MM (লেখক), Xiaojing Cheng, MM (লেখক), Rong Fu, MM (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2014-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: We aimed to investigate how losartan exerts protective effects on human umbilical vein endothelial cell injury induced by small, dense, LDL (sLDL) cholesterol particles. Methods: sLDL cholesterol was isolated by a 2-steps method and the nuclear translocation and activation of nuclear fact...