Synedrella nodiflora Extract Depresses Excitatory Synaptic Transmission and Chemically-Induced In Vitro Seizures in the Rat Hippocampus

• Main Authors: Patrick Amoateng (Author), Thomas A. Tagoe (Author), Thomas K. Karikari (Author), Kennedy K. E Kukuia (Author), Dorcas Osei-Safo (Author), Eric Woode (Author), Bruno G. Frenguelli (Author), Samuel B. Kombian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracts of the tropical Cinderella plant Synedrella nodiflora are used traditionally to manage convulsive conditions in the West African sub-region. This study sought to determine the neuronal basis of the effectiveness of these plant extracts to suppress seizure activity. Using the hippocampal sli...