Pharmacokinetic/Pharmacodynamic (PK/PD) Simulation for Dosage Optimization of Colistin Against Carbapenem-Resistant <i>Klebsiella pneumoniae</i> and Carbapenem-Resistant <i>Escherichia coli</i>

• Main Authors: Kamonchanok Jitaree (Author), Korbtham Sathirakul (Author), Jantana Houngsaitong (Author), Orarik Asuphon (Author), Weerayuth Saelim (Author), Visanu Thamlikitkul (Author), Preecha Montakantikul (Author)
• Format: Book
• Published: MDPI AG, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose was to explore the optimal dosage regimen of colistin using Monte Carlo simulations, for the treatment of carbapenem-resistant <i>Klebsiella pneumoniae</i> and carbapenem-resistant <i>Escherichia coli</i> based on PK/PD targets in critically ill patients. A total...