Pharmacokinetic/Pharmacodynamic (PK/PD) Simulation for Dosage Optimization of Colistin Against Carbapenem-Resistant <i>Klebsiella pneumoniae</i> and Carbapenem-Resistant <i>Escherichia coli</i>

• Egile Nagusiak: Kamonchanok Jitaree (Egilea), Korbtham Sathirakul (Egilea), Jantana Houngsaitong (Egilea), Orarik Asuphon (Egilea), Weerayuth Saelim (Egilea), Visanu Thamlikitkul (Egilea), Preecha Montakantikul (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2019-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The purpose was to explore the optimal dosage regimen of colistin using Monte Carlo simulations, for the treatment of carbapenem-resistant <i>Klebsiella pneumoniae</i> and carbapenem-resistant <i>Escherichia coli</i> based on PK/PD targets in critically ill patients. A total...