Synergy effects of copper ion in doxorubicin-based chelate prodrug for cancer chemo-chemodynamic combination therapy

AbstractDoxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application. It is shown that DOX-metal chelate has lower in vitro cytotoxicity compared with DOX, as the anthracyclines of DOX can form coordinati...

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Main Authors: Wen Zhang (Author), Peng Zhang (Author), Xiaopeng Xu (Author), Minghui Li (Author), Shasha Wang (Author), Hongjie Mu (Author), Kaoxiang Sun (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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