Cytochrome P450 2D6 genotype-phenotype characterization through population pharmacokinetic modeling of tedatioxetine

Abstract The cytochrome P450 (CYP) 2D6 enzyme exhibits large interindividual differences in metabolic activity. Patients are commonly assigned a CYP2D6 phenotype based on their CYP2D6 genotype, but there is a lack of consensus on how to translate genotypes into phenotypes, causing inconsistency in g...

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Main Authors: Trine Frederiksen (Author), Johan Areberg (Author), Ellen Schmidt (Author), Tore Bjerregaard Stage (Author), Kim Brøsen (Author)
Format: Book
Published: Wiley, 2021-09-01T00:00:00Z.
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