Detection of Anaplastic Lymphoma Kinase Gene Re-Arrangement in Non-Small Cell Lung Carcinoma in the Indian Population: Comparison of Techniques and Immunohistochemistry Clones

• Main Authors: Saumya SHUKLA (Author), Rahul Kumar PANDEY (Author), Surya KANT (Author), Rajiv GARG (Author), Nidhi ANAND (Author), Ram Awadh Singh KUSHWAHA (Author), Kiran Preet MALHOTRA (Author), Anand SRIVASTAVA (Author), Madan Lal Brahma BHATT (Author), Nuzhat HUSAIN (Author)
• Format: Book
• Published: Federation of Turkish Pathology Societies, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Predictive and prognostic markers have revolutionized personalized therapy in non-small cell lung carcinoma (NSCLC). Crizotinib is now approved for locally advanced or metastatic NSCLC that is anaplastic lymphoma kinase (ALK) positive by either Fluorescence in situ hybridization (FISH) or...