Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates.

• Main Authors: Stéphanie Reynard (Author), Emilie Gloaguen (Author), Nicolas Baillet (Author), Vincent Madelain (Author), Jérémie Guedj (Author), Hervé Raoul (Author), Xavier de Lamballerie (Author), Jimmy Mullaert (Author), Sylvain Baize (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ebola virus has been responsible for two major epidemics over the last several years and there has been a strong effort to find potential treatments that can improve the disease outcome. Antiviral favipiravir was thus tested on non-human primates infected with Ebola virus. Half of the treated animal...