Design and evaluation of magnetic-targeted bilosomal gel for rheumatoid arthritis: flurbiprofen delivery using superparamagnetic iron oxide nanoparticles

• Главные авторы: Rayan Y. Mushtaq (Автор), Nimbagal Raghavendra Naveen (Автор), Krishna Jayanth Rolla (Автор), Humood Al Shmrany (Автор), Sameer Alshehri (Автор), Ahmad Salawi (Автор), Mallesh Kurakula (Автор), Majed A. Alghamdi (Автор), Waleed Y. Rizg (Автор), Rana B. Bakhaidar (Автор), Walaa A. Abualsunun (Автор), Khaled M. Hosny (Автор), Abdulmohsin J. Alamoudi (Автор)
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• Опубликовано: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Предметы: article
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IntroductionThe study aimed to systematically enhance the fabrication process of flurbiprofen-loaded bilosomes (FSB) using Quality by Design (QbD) principles and Design of Experiments (DOE). The objective was to develop an optimized formulation with improved entrapment efficiency and targeted drug d...