Drug delivery systems based on biocompatible imino-chitosan hydrogels for local anticancer therapy

• Main Authors: Daniela Ailincai (Author), Liliana Tartau Mititelu (Author), Luminita Marin (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

A series of drug delivery systems were prepared by chitosan hydrogelation with citral in the presence of an antineoplastic drug: 5-fluorouracil. The dynamic covalent chemistry of the imine linkage allowed the obtaining of supramolecular tridimensional architectures in which the drug has been homogen...