Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations

• Автори: Tse-En J. Wang (Автор), Hung-Ting Liu (Автор), Yu-Hua Lai (Автор), Tong-Rong Jan (Автор), Naohiro Nomura (Автор), Hui-Wen Chang (Автор), Chi-Chung Chou (Автор), Ya-Jane Lee (Автор), Pei-Shiue J. Tsai (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Cisplatin is a potent anti-cancer drug that has been widely used in the treatment of various cancers; however, cisplatin administration results in severe nephrotoxicity and impedes its clinical applications. In this study, we showed that honokiol, a polyphenol constituent extracted from Magnolia off...