Counteracting protein kinase activity in the heart: The multiple roles of protein phosphatases

• Main Authors: Silvio eWeber (Author), Stefanie eMeyer-Roxlau (Author), Michael eWagner (Author), Dobromir eDobrev (Author), Ali eEl-Armouche (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Decades of cardiovascular research have shown that variable and flexible levels of protein phosphorylation are necessary to maintain cardiac function. A delicate balance between phosphorylated and dephosphorylated states of proteins is guaranteed by a complex interplay of protein kinases (PK) and ph...