BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?

• Prif Awduron: Tagliaferri Pierosandro (Awdur), Ventura Monica (Awdur), Baudi Francesco (Awdur), Cucinotto Iole (Awdur), Arbitrio Mariamena (Awdur), Di Martino Maria (Awdur), Tassone Pierfrancesco (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2009-10-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

<p>Abstract</p> <p>Ovarian epithelial tumors are an hallmark of hereditary cancer syndromes which are related to the germ-line inheritance of cancer predisposing mutations in BRCA1 and BRCA2 genes. Although these genes have been associated with multiple different physiologic functi...