Berberine Attenuates Cerebral Ischemia-Reperfusion Injury Induced Neuronal Apoptosis by Down-Regulating the CNPY2 Signaling Pathway

• Main Authors: Lina Zhao (Author), Huanming Li (Author), Qian Gao (Author), Jin Xu (Author), Yongjie Zhu (Author), Meili Zhai (Author), Peijun Zhang (Author), Na Shen (Author), Yanbo Di (Author), Jinhui Wang (Author), Tie Chen (Author), Meina Huang (Author), Jinglai Sun (Author), Chong Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine (BBR) has a neuroprotective effect against ischemic stroke, but its specific protective mechanism has not been clearly elaborated. This study explored the effect of BBR on the canopy FGF signaling regulator 2 (CNPY2) signaling pathway in the ischemic penumbra of rats. The model of cerebral...