Mimicking the Biology of Engineered Protein and mRNA Nanoparticle Delivery Using a Versatile Microfluidic Platform

• Main Authors: Valentina Palacio-Castañeda (Author), Rik Oude Egberink (Author), Arbaaz Sait (Author), Lea Andrée (Author), Benedetta Maria Sala (Author), Negar Hassani Besheli (Author), Egbert Oosterwijk (Author), Johan Nilvebrant (Author), Sander C. G. Leeuwenburgh (Author), Roland Brock (Author), Wouter P. R. Verdurmen (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To investigate the delivery of next-generation macromolecular drugs, such as engineered proteins and mRNA-containing nanoparticles, there is an increasing push towards the use of physiologically relevant disease models that incorporate human cells and do not face ethical dilemmas associated with ani...