STA9090 as a Potential Therapeutic Agent for Liver Fibrosis by Modulating the HSP90/TβRII/Proteasome Interplay: Novel Insights from In Vitro and In Vivo Investigations

• Main Authors: Osama A. Mohammed (Author), Mustafa Ahmed Abdel-Reheim (Author), Mohannad Mohammad S. Alamri (Author), Jaber Alfaifi (Author), Masoud I. E. Adam (Author), Lobna A. Saleh (Author), Alshaimaa A. Farrag (Author), Amar Ibrahim Omer Yahia (Author), Sameh Abdel-Ghany (Author), AbdulElah Al Jarallah AlQahtani (Author), Emad Bahashwan (Author), Hanan B. Eltahir (Author), Nahid A. Mohammed (Author), Hend S. El-wakeel (Author), Sara H. Hazem (Author), Sameh Saber (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis is a progressive condition characterized by the build-up of fibrous tissue resulting from long-term liver injury. Although there have been advancements in research and treatment, there is still a need for effective antifibrotic medication. HSP90 plays a crucial role in the development...