Electrostatic spraying for fine-tuning particle dimensions to enhance oral bioavailability of poorly water-soluble drugs

• Main Authors: Jung Suk Kim (Author), Seunghyun Cheon (Author), Mi Ran Woo (Author), Sanghyun Woo (Author), Jee-Eun Chung (Author), Yu Seok Youn (Author), Kyung Taek Oh (Author), Soo-Jeong Lim (Author), Sae Kwang Ku (Author), Bao Loc Nguyen (Author), Jong Oh Kim (Author), Sung Giu Jin (Author), Han-Gon Choi (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While spray-drying has been widely utilized to improve the bioavailability of poorly water-soluble drugs, the outcomes often exhibit suboptimal particle size distribution and large particle sizes, limiting their effectiveness. In this study, we introduce electrostatic spraying as an advanced technol...