A Phase 1 Study to Assess the Pharmacokinetics, Food Effect, Safety, and Tolerability of Sepiapterin in Healthy Japanese and Non-Japanese Participants

Background: Sepiapterin is a natural precursor of tetrahydrobiopterin (BH<sub>4</sub>), a key cofactor for phenylalanine hydroxylase. It is being developed for the treatment of patients with phenylketonuria. In this study, the ethnic differences in pharmacokinetics and safety of sepiapte...

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Main Authors: Lan Gao (Author), Diksha Kaushik (Author), Kimberly Ingalls (Author), Neil Smith (Author), Ronald Kong (Author)
Format: Book
Published: MDPI AG, 2024-10-01T00:00:00Z.
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