Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration

• Автори: Tian Lan (Автор), Yang Tai (Автор), Chong Zhao (Автор), Yang Xiao (Автор), Zhu Yang (Автор), Linhao Zhang (Автор), Can Gan (Автор), Wenting Dai (Автор), Huan Tong (Автор), Chengwei Tang (Автор), Zhiyin Huang (Автор), Jinhang Gao (Автор)
• Формат: Книга
• Опубліковано: BMC, 2023-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Hepatocyte-cholangiocyte transdifferentiation (HCT) is a potential origin of proliferating cholangiocytes in liver regeneration after chronic injury. This study aimed to determine HCT after chronic liver injury, verify the impacts of HCT on liver repair, and avoid harmful regener...