Molecular computations of preferential interactions of proline, arginine.HCl, and NaCl with IgG1 antibodies and their impact on aggregation and viscosity

Preferential interactions of excipients with the antibody surface govern their effect on the stability of antibodies in solution. We probed the preferential interactions of proline, arginine.HCl (Arg.HCl), and NaCl with three therapeutically relevant IgG1 antibodies via experiment and simulation. Wi...

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主要な著者: Theresa K. Cloutier (著者), Chaitanya Sudrik (著者), Neil Mody (著者), Sathish A. Hasige (著者), Bernhardt L. Trout (著者)
フォーマット: 図書
出版事項: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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請求記号: A1234.567
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