Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21Waf1/Cip1 and p27Kip1

Objective: Carfilzomib is a second-generation tetrapeptide epoxyketone proteasome inhibitor used in current clinical therapy of hematologic malignancies. The mechanism of proteasome inhibition in endometrial cancer is not very clear. Carfilzomib inhibition of type I endometrial carcinoma cell prolif...

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Main Authors: Yuanyuan Zhou (Author), Ke Wang (Author), Shuai Zhen (Author), Ruili Wang (Author), Wenjuan Luo (Author)
Format: Book
Published: Elsevier, 2016-12-01T00:00:00Z.
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