Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study

Abstract Measuring muscle velocity recovery cycles (MVRCs) is a method to obtain information on muscle cell excitability, independent of neuromuscular transmission. The goal was to validate MVRC as a pharmacodynamic (PD) biomarker for drugs targeting muscle excitability. As proof‐of‐concept, sensiti...

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Main Authors: Titia Q. Ruijs (Author), Ingrid W. Koopmans (Author), Marieke L. deKam (Author), Martijn R. Tannemaat (Author), Geert Jan Groeneveld (Author), Jules A. A. C. Heuberger (Author)
Format: Book
Published: Wiley, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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