Definition of miRNA Signatures of Nodal Metastasis in LCa: miR-449a Targets Notch Genes and Suppresses Cell Migration and Invasion

• Main Authors: Hiromichi Kawasaki (Author), Takashi Takeuchi (Author), Filippo Ricciardiello (Author), Angela Lombardi (Author), Elia Biganzoli (Author), Marco Fornili (Author), Davide De Bortoli (Author), Massimo Mesolella (Author), Alessia Maria Cossu (Author), Marianna Scrima (Author), Rosanna Capasso (Author), Michela Falco (Author), Giovanni Motta (Author), Gaetano Motta (Author), Domenico Testa (Author), Stefania De Luca (Author), Flavia Oliva (Author), Teresa Abate (Author), Salvatore Mazzone (Author), Gabriella Misso (Author), Michele Caraglia (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Laryngeal cancer (LCa), a neoplasm of the head and neck region, is a leading cause of death worldwide. Surgical intervention remains the mainstay of LCa treatment, but a crucial point is represented by the possible nodal involvement. Therefore, it is urgently needed to develop biomarkers and therape...