Serum IgG antibodies to Shigella lipopolysaccharide antigens - a correlate of protection against shigellosis

• Main Authors: Dani Cohen (Author), Shiri Meron-Sudai (Author), Anya Bialik (Author), Valeria Asato (Author), Sophy Goren (Author), Ortal Ariel-Cohen (Author), Arava Reizis (Author), Amit Hochberg (Author), Shai Ashkenazi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Shigella is a leading cause of diarrhea among children globally and of diarrheal deaths among children under 5 years of age in low- and middle-income countries. To date, no licensed Shigella vaccine exists. We review evidence that serum IgG antibodies to Shigella LPS represent a good correlate of pr...