Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

• Main Authors: Brahmi Dalel (Author), Ayed Yousra (Author), Hfaiedh Mbarka (Author), Bouaziz Chayma (Author), Mansour Hedi Ben (Author), Zourgui Lazhar (Author), Bacha Hassen (Author)
• Format: Book
• Published: BMC, 2012-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Cis-Platinum (II) (cis-diammine dichloroplatinum; CDDP) is a potent antitumor compound widely used for the treatment of many malignancies. An important side-effect of CDDP is nephrotoxicity. The cytotoxic action of this drug is often...