Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study

• Main Authors: Guilherme Grossi Lopes Cançado (Author), Cláudia Alves Couto (Author), Laura Vilar Guedes (Author), Michelle Harriz Braga (Author), Débora Raquel Benedita Terrabuio (Author), Eduardo Luiz Rachid Cançado (Author), Maria Lucia Gomes Ferraz (Author), Cristiane Alves Villela-Nogueira (Author), Mateus Jorge Nardelli (Author), Luciana Costa Faria (Author), Elze Maria Gomes de Oliveira (Author), Vivian Rotman (Author), Daniel Ferraz de Campos Mazo (Author), Valéria Ferreira de Almeida e Borges (Author), Liliana Sampaio Costa Mendes (Author), Liana Codes (Author), Mario Guimarães Pessoa (Author), Izabelle Venturini Signorelli (Author), Cynthia Levy (Author), Paulo Lisboa Bittencourt (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Up to 40% of patients with primary biliary cholangitis (PBC) will have a suboptimal biochemical response to ursodeoxycholic acid (UDCA), which can be improved by the addition of fibrates. This exploratory study aims to evaluate the long-term real-life biochemical response of different fibrates,...