Salsolinol Attenuates Doxorubicin-Induced Chronic Heart Failure in Rats and Improves Mitochondrial Function in H9c2 Cardiomyocytes

• Main Authors: Jianxia Wen (Author), Lu Zhang (Author), Honghong Liu (Author), Jiabo Wang (Author), Jianyu Li (Author), Yuxue Yang (Author), Yingying Wang (Author), Huadan Cai (Author), Ruisheng Li (Author), Yanling Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Backgrounds: Salsolinol (SAL), a plant-based isoquinoline alkaloid, was initially isolated from Aconiti Lateralis Radix Praeparata (ALRP) and identified as the active cardiotonic component of ALRP. This study was aimed to explore the therapeutic effect and mechanism by which SAL attenuates doxorubic...