Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.

• Main Authors: Thomas R Lane (Author), Christopher Massey (Author), Jason E Comer (Author), Manu Anantpadma (Author), Joel S Freundlich (Author), Robert A Davey (Author), Peter B Madrid (Author), Sean Ekins (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent outbreaks of the Ebola virus (EBOV) have focused attention on the dire need for antivirals to treat these patients. We identified pyronaridine tetraphosphate as a potential candidate as it is an approved drug in the European Union which is currently used in combination with artesunate as a tr...