Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.

• Prif Awduron: Thomas R Lane (Awdur), Christopher Massey (Awdur), Jason E Comer (Awdur), Manu Anantpadma (Awdur), Joel S Freundlich (Awdur), Robert A Davey (Awdur), Peter B Madrid (Awdur), Sean Ekins (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Recent outbreaks of the Ebola virus (EBOV) have focused attention on the dire need for antivirals to treat these patients. We identified pyronaridine tetraphosphate as a potential candidate as it is an approved drug in the European Union which is currently used in combination with artesunate as a tr...