Celecoxib to improve scar quality following acute burn injury: Lessons learned after premature termination of a randomised trial

• Main Authors: Edward Raby (Author), Paul Gittings (Author), Edward Litton (Author), Aaron Berghuber (Author), Dale Wesley Edgar (Author), Jo Camilleri (Author), Kris Owen (Author), Rosemary Kendell (Author), Laurens Manning (Author), Mark Fear (Author), Fiona Melanie Wood (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pre-clinical studies suggest that non-steroidal anti-inflammatory therapy may reduce acute inflammation and modulate scar formation after burn injury. The objective of this trial was to determine if celecoxib administered soon after acute burn improved scar quality. Methods: A single cen...