Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NF-κB Signaling Pathways

• Main Authors: Mohamed A. Morsy (Author), Yasmine F. Ibrahim (Author), Sara Mohamed Naguib Abdel Hafez (Author), Nagwa M. Zenhom (Author), Anroop B. Nair (Author), Katharigatta N. Venugopala (Author), Pottathil Shinu (Author), Seham A. Abdel-Gaber (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several clinical situations. Modulating oxidative stress and inflammation by Nrf2/HO-1 and TLR4/MYD88/NF-κB pathways, respectively, is involved in alleviating HIR injury. Paeonol is a natural phenolic compound that...