Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

• Main Authors: Armel Jackson Seukep (Author), Victor Kuete (Author), Lutfun Nahar (Author), Satyajit D. Sarker (Author), Mingquan Guo (Author)
• Format: Bog
• Udgivet: Elsevier, 2020-08-01T00:00:00Z.
• Fag: article
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The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The major factor in MDR is efflux pump-mediated resistance. A unique pump can make bacteria withstand a wide range of str...