Dual effect of reduced type I diacylglycerol kinase activity on insulin secretion from MIN6 β-cells

The role of type I diacylglycerol kinases (DGKs) in the regulation of insulin secretion was investigated in MIN6 β-cells. In intracellular Ca2+ concentration ([Ca2+]i) measurement experiments, 1 μM R59949, a type I DGK inhibitor, and 10 μM DiC8, a diacylglycerol (DAG) analog, amplified 22.2 mM gluco...

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Main Authors: Toshiaki Sawatani (Author), Yukiko K. Kaneko (Author), Tomohisa Ishikawa (Author)
Format: Book
Published: Elsevier, 2019-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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