Modulation of the photobehavior of gefitinib and its phenolic metabolites by human transport proteins

• Main Authors: Lorena Tamarit (Author), Meryem El Ouardi (Author), Emilio Lence (Author), Inmaculada Andreu (Author), Concepcion González-Bello (Author), Miguel A. Miranda (Author), Ignacio Vayá (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The photobiological damage that certain drugs or their metabolites can photosensitize in proteins is generally associated with the nature of the excited species that are generated upon interaction with UVA light. In this regard, the photoinduced damage of the anticancer drug gefitinib (GFT) and its...