PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice

• Auteurs principaux: Zhonghao Bai (Auteur), Wen Yin (Auteur), Rui Liu (Auteur), Minglei Tang (Auteur), Xiaofeng Shi (Auteur), Cheng Luo (Auteur), Xiangyang Xie (Auteur)
• Format: Livre
• Publié: Elsevier, 2023-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective: Peroxiredoxin 1 (PRDX1) is a peroxidase and guards against oxidative stress by scavenging intracellular peroxides, whereas it also has been shown to stimulate inflammatory response by functioning as a chaperone protein. The potential in vivo link between PRDX1's peroxidase activity a...