Synthesis and Impurity Research of 2-Thioadenosine Monohydrate

Abstract 2-Thioadenosine monohydrate (1) is a vital intermediate in the synthesis of cangrelor. However, its industrial-scale preparation process and the analysis of the impurities formed during this process remained largely unknown. Herein, cangrelor was synthesized from oxidate adenosine, and the...

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Main Authors: Jing-Jing Xiang (Author), Bi-Bo Jiang (Author), Wen-Qing Sun (Author), Fu-Li Zhang (Author), Jun Yu (Author)
Format: Book
Published: Georg Thieme Verlag KG, 2023-06-01T00:00:00Z.
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