The therapeutic potential of the novel ribonuclease ranpirnase (Onconase®) in the treatment of malignant mesothelioma

Ribonucleases are a superfamily of RNA-cleaving enzymes that can be cytotoxic since the cleavage of RNA makes its information indecipherable. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA, thus leading to an inhibition of protein synthesis and, ultimately, to cytostasis and c...

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Main Authors: Luciano Mutti (Author), Giovanni Gaudino (Author)
Format: Book
Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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