Exploring Antibiotic-Potentiating Effects of Tobramycin-Deferiprone Conjugates in <i>Pseudomonas aeruginosa</i>

• Main Authors: Karan Gandhi (Author), Shiv Dhiman (Author), Rajat Arora (Author), Danzel Marie Ramirez (Author), Danyel Ramirez (Author), Gilbert Arthur (Author), Frank Schweizer (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2023-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Metal ions, including Fe³⁺, affect the target site binding of some antibiotics and control the porin- and siderophore-mediated uptake of antibiotics. Amphiphilic tobramycins are an emerging class of antibiotic potentiators capable of synergizing with multiple classes of antibi...